Found 19 matching trials
Comparison of Three Plasmodium Falciparum Isolates in an Experimental Human Malaria Infection
NAPlasmodium falciparum isolates display a wide genetic diversity with possib...
Location
Leiden University Medical Center
Evaluate the Infectivity Equivalence of Current and New Lots of Plasmodium Falciparum Strain NF54
PHASE1Objectives:
Primary:
• To characterize the infectivity of the new lot of ...
Location
Walter Reed Army Institute of Research
Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites
PHASE1This Phase 1 trial will include 16 subjects who will receive the Geneticall...
Location
Kaiser Permanente Washington Health Research Institute
Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under Chemoprophylaxis
NAMalaria, a disease caused by the parasite Plasmodium, is one of the world's...
Location
Radboud university medical center
Trial to Evaluate L9LS in Healthy Adults
PHASE1Background:
Malaria is a parasitic disease carried by mosquitoes in tropic...
Location
National Institutes of Health Clinical Center
Safety and Causal Prophylactic Efficacy of KAF156 in a Controlled Human Malaria Challenge Model
PHASE1This study is designed to investigate the safety and causal prophylactic ef...
Location
Novartis Investigative Site
Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection
NAMalaria, a disease caused by the parasite Plasmodium, is one of the world's...
Location
Radboud university medical center
Safety and Efficacy of NF135 CPS Immunization
NAThis is an open label, randomized, controlled clinical trial. The primary a...
Location
Radboud university medical centre
Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis
PHASE1This study will assess the superior protective immunity of the combination ...
Location
Leiden University Medical Centre
Safety and Preliminary Protective Efficacy of Genetically Attenuated GA2 Parasites.
PHASE1This study will consist of two phases and be aimed at assessing the safety ...
Location
Leiden University Medical Center